Company description
LRRK2 protein is composed of seven functional domains: ANK, LRR, ROC, CDR, MAPKKK~H, and WD-40. Among them, ANK, LRR~H WD-40 are involved in protein interactions, ANKs are found in both prokaryotes and eukaryotes, and LRR can be involved in mediating GTPase and protein kinase activities. The gene mutation of the LR domain is closely related to the occurrence of Parkinson’s disease.