Non-homologous End-joining Pathway

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Address:
400 Oxford Street
London 11967
England
United Kingdom
Phone number:
16316197922

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Company description

DNA double-strand break (DSB) is one of the most dangerous forms of DNA damage. Unrepaired DSBs will lead cells to undergo apoptosis or senescence. On the other side, mis-processing of DSBs will also result in genomic instability and carcinogenesis. Non-homologous end-joining (NHEJ) is one important pathway in eukaryotic cells responsible for the repair of DSBs.

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